Selected Publications

Shin H, Chung H. SMPDL3A links cholesterol metabolism to the cGAS-STING pathway. Immunity. 2023 Nov 14;56(11):2459-2461. doi: 10.1016/j.immuni.2023.10.015. PMID: 37967525.

Dorrity TJ, Chung H. A tale of two pathways: Two distinct mechanisms of ADAR1 prevent fatal autoinflammation. Mol Cell. 2023 Nov 2;83(21):3760-3762. doi: 10.1016/j.molcel.2023.10.005. PMID: 37922869.

Dorrity TJ, Shin H, Wiegand KA, Aruda J, Closser M, Jung E, Gertie JA, Leone A, Polfer R, Culbertson B, Yu L, Wu C, Ito T, Huang Y, Steckelberg AL, Wichterle H, Chung H. Long 3'UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation. Sci Immunol. 2023 Oct 27;8(88):eadg2979. doi: 10.1126/sciimmunol.adg2979. Epub 2023 Oct 20. PMID: 37862432.

Sun T, Rosenberg BR, Chung H, Rice CM. Identification of ADAR1 p150 and p110 Associated Edit Sites. Methods Mol Biol. 2023;2651:285-294. doi: 10.1007/978-1-0716-3084-6_20.

Sun T, Yu Y, Wu X, Acevedo A, Luo JD, Wang J, Schneider WM, Hurwitz B, Rosenberg BR, Chung H*, Rice CM*. Decoupling expression and editing preferences of ADAR1 p150 and p110 isoforms. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2021757118.

*co-corresponding authors

Nair L, Chung H, Basu U. Regulation of long non-coding RNAs and genome dynamics by the RNA surveillance machinery. Nat Rev Mol Cell Biol. 2020 Mar;21(3):123-136. 

Chung H, Rice CM. T time for ADAR: ADAR1 is required for T cell self-tolerance. EMBO Rep. 2018 Dec;19(12). 

Chung H, Calis JJA, Wu X, Sun T, Yu Y, Sarbanes SL, Dao Thi VL, Shilvock AR, Hoffmann HH, Rosenberg BR, Rice CM. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. Cell. 2018 Feb 8; 172 (4):811-824.e14.

Yu Y, Scheel TKH, Luna JM, Chung H, Nishiuchi E, Scull MA, Echeverría N, Ricardo-Lax I, Kapoor A, Lipkin WI, Divers TJ, Antczak DF, Tennant BC, Rice CM. miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence. PLoS Pathog. 2017 Oct;13(10):e1006694. 

Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR, Umesaki Y, Mathis D, Benoist C, Relman DA, Kasper DL. Gut immune maturation depends on colonization with a host-specific microbiota. Cell. 2012 Jun 22;149(7):1578-93.

Chung H, Kasper DL. Microbiota-stimulated immune mechanisms to maintain gut homeostasis. Curr Opin Immunol. 2010 Aug;22(4):455-60. 

Duan J, Chung H, Troy E, Kasper DL. Microbial colonization drives expansion of IL-1 receptor 1-expressing and IL-17-producing gamma/delta T cells. Cell Host Microbe. 2010 Feb 18;7(2):140-50.

Gryllos I, Tran-Winkler HJ, Cheng MF, Chung H, Bolcome R 3rd, Lu W, Lehrer RI, Wessels MR. Induction of group A Streptococcus virulence by a human antimicrobial peptide. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16755-60. 

Ryndak MB, Chung H, London E, Bliska JB. Role of predicted transmembrane domains for type III translocation, pore formation, and signaling by the Yersinia pseudotuberculosis YopB protein. Infect Immun. 2005 Apr;73(4):2433-43.